Fibroblasts play a central role in maintaining healthy tissue structures, as well as in the development and progression of diseases. For a long time, these specialized connective tissue cells were thought to represent a single, uniform cell type. A recent publication shows that fibroblasts in human tissue actually consist of distinct populations with specialized functions. This heterogeneity is key to developing targeted therapies in regenerative medicine and in the treatment of diseases.
Read more …New perspectives for wound healing and the treatment of chronic diseases

Head and neck cancer researchers are reporting the development and testing of HPV-DeepSeek, a novel liquid biopsy assay. In their new study, HPV-DeepSeek achieved 99% sensitivty and specifity for diagnosing HPV-associated head and neck cancers, outperforming standard of care methods. HPV causes about 70% of oropharyngeal cancers in the U.S., which are increasing in incidence faster than other head and neck cancers.
Read more …New blood test shows superior sensitivity in detecting HPV-associated head and neck cancers

a girl with brightly colored prosthetic hands walks beside a woman pushing a baby in a stroller

Three-dimensional printing is transforming medical care, letting the health care field shift from mass-produced solutions to customized treatments tailored to each patient’s needs. For instance, researchers are developing 3D-printed prosthetic hands[1] specifically designed for children, made with lightweight materials and adaptable control systems.

These continuing advancements in 3D-printed prosthetics demonstrate their increasing...

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