A study demonstrates the role of the Galectin-1 protein in the nucleus of the cells surrounding the tumor -- fibroblasts -- contributing to their activation. Activated fibroblasts promote tumor growth and spread, while also conferring resistance to treatments. This may be one of the reasons behind the high aggressiveness of pancreatic cancer, which has a five-year survival rate of only 10%. The study's findings open the door to new therapeutic strategies against this type of cancer, focusing on the possibility of inhibiting this protein within the cells that surround and protect the tumor.
Read more …Key to the high aggressiveness of pancreatic cancer identified
Researchers have developed a machine learning workflow to optimize the output force of photo-actuated organic crystals. Using LASSO regression to identify key molecular substructures and Bayesian optimization for efficient sampling, they achieved a maximum blocking force of 37.0 mN -- 73 times more efficient than conventional methods. These findings could help develop remote-controlled actuators for medical devices and robotics, supporting applications such as minimally invasive surgery and precision drug delivery.
Read more …Machine learning unlocks superior performance in light-driven organic crystals
The human brain can learn through experience to filter out disturbing and distracting stimuli -- such as a glaring roadside billboard or a flashing banner on the internet. Scientists have used electroencephalography (EEG) to show that early visual processing in humans changes with repeated exposure.
Read more …The brain learns to filter out distracting stimuli over time