New research combines two powerful imaging techniques to study the complete structure of a common aGPCR, including how its long and complex extracellular region interacts with the transmembrane region embedded in the cell surface. The different positions and movements of the extracellular region appear to be an important way to activate the receptor.
Read more …Images of crucial cell receptors show promising new drug targets
Almost three quarters of adolescents in Australia experience clinically significant depression or anxiety symptoms, with most being chronic, according to a new study. And preventive strategies outside our clinics are urgently required to address this considerable public health problem facing the nation.
Read more …Almost three quarters of adolescents experience depression or anxiety