A heart attack will leave a permanent scar on a human heart, yet other animals, including zebrafish, can clear cardiac scar tissue and regrow damaged muscle as adults. Biologists sheds new light on how zebrafish heal heart tissue by comparing how this species responds to heart injury with medaka, a fish species that cannot regenerate cardiac tissue.
Read more …Why can zebrafish regenerate damaged heart tissue, while other fish species cannot?

Despite progress in defining functional elements of noncoding DNA, it is still not fully understood. Researchers, using an experiment that elucidated the function of tens of thousands of noncoding variants, discovered a link between functional mutations and genes linked to cancer pathways, as well as indicators to predict cancer patient survival. Understanding the mutations' influence on mRNA and protein production could shed light on the processes that drive cancer progression and guide advancement of testing tools.
Read more …Mutations in noncoding DNA become functional in some cancer-driving genes

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