Meditation is now widely promoted as a tool for everything from reducing stress to improving productivity. It has become a go-to approach for supporting mental well-being across many settings.

However, when a practice like meditation is used in medical or therapeutic contexts, important scientific questions arise. How much practice is needed to produce benefits? And just as critically, are there any risks or unwanted side effects associated with it?

"This is the kind of research that is done at the very beginning of developing any new treatment intervention program," explained Nicholas Van Dam, a psychologist at the University of Melbourne. "And for various complex reasons, with mindfulness-based programs in particular, that just didn't happen."

Exploring the Possible Downsides of Meditation

While many people report positive outcomes, research over the years has also revealed that meditation can lead to adverse experiences for some individuals. These side effects may include panic attacks, intrusive or distressing memories related to past trauma (as seen in post-traumatic stress disorder), and in more extreme cases, sensations of depersonalization or dissociation.

Van Dam noted that estimates of how common these experiences are vary widely in the scientific literature. Some studies suggest that only about 1% of meditators experience side effects (Wong et al., 2018), whereas others report figures as high as two thirds (Britton et al., 2021).

To clarify these inconsistencies, Van Dam and his colleagues conducted a study published in Clinical Psychological Science to investigate how frequently meditators encounter side effects and what factors might increase the likelihood of experiencing them.

A Nationwide Study of Meditation Experiences

The research team recruited nearly 900 adults from across the United States. To ensure the group reflected the broader U.S. population of meditators, they used data from the Centers for Disease Control and Prevention to guide participant selection. The researchers also recruited meditators from a wide range of skill levels, from beginner to advanced, "such that we could kind of get a sense of the full sample of people who engage in meditation within the U.S.," Van Dam said.

Van Dam emphasized that the way researchers ask about side effects can dramatically influence the findings. "The devil is in the details," he said, explaining that many previous studies rely on open-ended questions, a method known as spontaneous reporting. In such cases, participants might not recognize their experiences as side effects or may hesitate to mention them.

To reduce that uncertainty, Van Dam's team developed a 30-item checklist covering possible effects of meditation. Participants rated the intensity of each effect, whether it was positive or negative, and whether it interfered with their daily functioning.

What the Data Revealed

The results showed that nearly 60% of U.S. meditators reported at least one side effect listed on the checklist (for example, feeling anxious or disembodied). About 30% said they experienced effects that were challenging or distressing, and 9% reported that these effects caused functional impairment.

The study also identified several potential risk factors. Individuals who had experienced mental health symptoms or psychological distress within the 30 days before meditating were more likely to report adverse effects. Those who attended intensive residential retreats, which often involve long periods of silent meditation, were also more likely to experience functional impairment.

Van Dam noted that more research is needed to determine cause and effect. A prospective longitudinal study, he said, would help clarify how mental health and meditation interact over time.

Encouraging Awareness, Not Fear

Despite these findings, Van Dam cautioned against viewing meditation as dangerous. "Our conclusions are not that people should be terrified, or people should not try meditation. It's really that we think that we should do a better job of providing informed consent," he said.

He compared the situation to other therapeutic treatments, such as surgery or exposure therapy, where patients are told in advance what they might experience. This preparation allows individuals to weigh risks and make informed decisions about their participation.

Navigating Discomfort in Mindfulness Practice

In meditation, this kind of pre-discussion often doesn't happen. "We have to find a way to have that conversation and navigate that space," Van Dam said. He suggested that practitioners and clinicians should explain that discomfort can sometimes be part of the process. Feelings of unease or questioning one's sense of self are not necessarily signs of harm but rather potential aspects of deep psychological exploration. However, distress that significantly interferes with daily functioning should be taken seriously.

"These practices are not for everyone," Van Dam concluded. "If they're not working, it's not necessarily because the person is doing something wrong. It might be because it's just not a good match."

Read more …Scientists uncover meditation’s hidden side effects

  • Most Americans don't realize the cancer risks of alcohol. More than half of U.S. adults either underestimate or misunderstand how drinking increases cancer risk.
  • Regular drinkers are the least aware. People who consume alcohol are especially likely to believe that drinking has no impact on cancer risk.
  • Better awareness could save lives. Educating the public about the real link between alcohol and cancer may help more people follow the U.S. Surgeon General's guidelines and reduce preventable cancer cases.

Many Americans Unaware of Alcohol's Cancer Risk

New research from The University of Texas MD Anderson Cancer Center shows that public understanding of the connection between alcohol and cancer remains surprisingly low in the United States. Despite decades of scientific evidence, more than half of American adults (52.9%) were unaware that alcohol affects cancer risk.

The findings, published October 30 in JAMA Oncology, reveal that only 37.1% of adults recognized that drinking alcohol raises cancer risk, while 1% believed it actually lowers it. The study also noted that individuals who had consumed alcohol recently, or who thought cancer was not fatal or preventable, were more likely to say that alcohol has no influence on cancer risk.

Lead author Sanjay Shete, Ph.D., professor of Biostatistics and Epidemiology and Betty B. Marcus Chair in Cancer Prevention, called the results alarming. "It's concerning that people who drink alcohol are the ones most likely to believe it has no effect on cancer risk," Shete said. "Given people's beliefs play a critical role in whether they choose healthier behaviors, we need to work on correcting these misperceptions, which could be essential to reducing the growing burden of alcohol-related cancers."

Researchers examined what influences how people view alcohol and cancer risk, noting that health-related behaviors and beliefs strongly affect whether individuals make informed choices. The study found that certain demographic and behavioral traits were linked to greater misunderstanding of alcohol's effects.

Current cigarette smokers, Black individuals, those with lower levels of education (below a college or high school level), and people who do not believe cancer can be prevented were more likely to say they did not know alcohol contributes to cancer risk.

Alcohol's Proven Role as a Carcinogen

The World Health Organization classifies alcohol as a Group 1 carcinogen, the same level of risk as tobacco, asbestos, and radiation. Alcohol consumption has been tied to at least seven types of cancer, including breast, liver, and colorectal cancers. According to the National Institutes of Health (NIH), drinking alcohol accounts for about 5.5% of all new cancer cases and 5.8% of all cancer deaths worldwide.

Researchers suggest that correcting misinformation could help more people follow alcohol consumption guidelines, including those endorsed by the U.S. Surgeon General in his 2025 advisory, potentially reducing preventable cancer-related deaths.

The analysis drew on data from nearly 7,000 adults aged 18 and older (mean age 48) who participated in the 2024 Health Information National Trends Survey. Among respondents, 48.4% were female, 60.7% identified as white, 17.5% as Hispanic, and 11% as Black. Over half reported drinking alcohol within the past month, and almost 10% had a personal history of cancer.

Participants were asked, "In your opinion, how does drinking alcohol affect the risk of getting cancer?" They could choose from four responses: "decreases the risk of cancer," "has no effect on the risk of cancer," "increases risk of cancer," and "don't know."

This research was supported by the National Cancer Institute (P30CA016672) and the Betty B. Marcus Chair in Cancer Prevention. A complete list of authors, disclosures, and funding sources is available in the full JAMA Oncology article.

Read more …Most Americans don’t know alcohol can cause cancer

Protecting public health abroad benefits Americans.

In a globalized world, diseases and their social and economic impacts do not stay within national boundaries[1]. Increased rates of untreated HIV in any part of the world increase the risk of transmission for U.S. citizens.

Changes made in the first year of President Donald Trump’s second term to address the global HIV epidemic, however, may not keep Americans safe.

In...

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  • Viruses are masters of efficiency, able to take over our cells and control vital processes using only a handful of genes.
  • For years, scientists have wondered how something so small could do so much.
  • Researchers have now uncovered the answer -- a discovery that could reshape our understanding of how viruses work and lead to new ways to fight them.

Breakthrough Reveals How Viruses Outsmart Human Cells

A team of Australian scientists has uncovered how certain viruses manage to seize control of human cells, a finding that could lead to the next generation of antivirals and vaccines.

The research, led by Monash University and the University of Melbourne and published in Nature Communications, explains how the rabies virus can manipulate a wide range of cellular activities despite producing only a few proteins.

Scientists believe this same mechanism could also be at work in other deadly pathogens, including Nipah and Ebola viruses. If so, the discovery could pave the way for new treatments that block these viral strategies.

How Viruses Do So Much With So Little

Co-senior author Associate Professor Greg Moseley, head of the Monash Biomedicine Discovery Institute's (BDI) Viral Pathogenesis Laboratory, described the remarkable efficiency of viruses.

"Viruses such as rabies can be incredibly lethal because they take control of many aspects of life inside the cells they infect," Associate Professor Moseley said. "They hijack the machinery that makes proteins, disrupt the 'postal service' that sends messages between different parts of the cell, and disable the defenses that normally protect us from infection."

He explained that scientists have long puzzled over how viruses with such limited genetic material could be so powerful. "Rabies virus, for example, has the genetic material to make only five proteins, compared with about 20,000 in a human cell," he said.

The Key: A Shape-Shifting Viral Protein

Co-first author Dr. Stephen Rawlinson, a research fellow in the Moseley Lab, said the team's work offers a long-sought answer.

"Our study provides an answer," he said. "We discovered that one of rabies virus's key proteins, called P protein, gains a remarkable range of functions through its ability to change shape and to bind to RNA."

"RNA is the same molecule used in new-generation RNA vaccines, but it plays essential roles inside our cells, carrying genetic messages, coordinating immune responses, and helping make the building blocks of life."

Taking Over the Cell's Inner World

Co-senior author Professor Paul Gooley, who leads the University of Melbourne's Gooley Laboratory, said the viral P protein's ability to interact with RNA allows it to shift between different physical 'phases' within a cell.

"This allows it to infiltrate many of the cell's liquid-like compartments, take control of vital processes, and turn the cell into a highly efficient virus factory," Professor Gooley said.

Although this research focused on rabies, he noted that similar tactics may be used by other deadly viruses, including Nipah and Ebola. "Understanding this new mechanism opens exciting possibilities for developing antivirals or vaccines that block this remarkable adaptability," he added.

Rethinking How Viral Proteins Work

Dr. Rawlinson said the findings challenge how scientists have traditionally viewed multifunctional viral proteins. "Until now, these proteins were often viewed like trains made up of several carriages, with each carriage (or module) responsible for a specific task," he said.

"According to this view, shorter versions of a protein should simply lose functions as carriages are removed. However, this simple model could not explain why some shorter viral proteins actually gain new abilities. We found that multifunctionality can also arise from the way the 'carriages' interact and fold together to create different overall shapes, as well as forming new abilities such as binding to RNA."

A New Perspective on Viral Adaptability

Associate Professor Moseley said that the ability of the P protein to bind RNA allows it to move between different physical 'phases' inside the cell.

"In doing so, it can access and manipulate many of the cell's own liquid-like compartments that control key processes, such as immune defense and protein production," he said. "By revealing this new mechanism, our study provides a fresh way of thinking about how viruses use their limited genetic material to create proteins that are flexible, adaptable, and able to take control of complex cellular systems."

This study involved Monash University, the University of Melbourne, the Australian Nuclear Science and Technology Organisation (Australian Synchrotron), Peter Doherty Institute for Infection and Immunity, Commonwealth Scientific and Industrial Research Organisation (CSIRO), the Australian Centre for Disease Preparedness (ACDP), and Deakin University.

Read more …A shapeshifting protein explains rabies’ deadly power

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