Researchers have discovered a process that breaks down mRNA molecules in the human body particularly efficiently. This could be useful, for example, in the treatment of cancer.
Read more …A quick end for mRNA
A study is the first-of-its-kind to recognize American Sign Language (ASL) alphabet gestures using computer vision. Researchers developed a custom dataset of 29,820 static images of ASL hand gestures. Each image was annotated with 21 key landmarks on the hand, providing detailed spatial information about its structure and position. Combining MediaPipe and YOLOv8, a deep learning method they trained, with fine-tuning hyperparameters for the best accuracy, represents a groundbreaking and innovative approach that hasn't been explored in previous research.
Read more …Breaking barriers: Study uses AI to interpret American Sign Language in real-time
Craniopharyngiomas are brain tumors that negatively impact the hormonal function of the nearby pituitary. The tumor location often prevents necessary surgical intervention. Alternative pharmacological therapy requires an in-depth understanding of the tumor molecular characteristics. To address this gap, researchers analyzed gene expression within individual tumor cells. This study reports the molecular features and interactions of tumor and immune cells associated with two craniopharyngioma subtypes that will help identify future targeted therapeutics.
Read more …Every cell has a story: Tumor and immune cell interactions within craniopharyngiomas
Prostate cancer, especially in advanced stages such as castration-resistant prostate cancer, is challenging to treat. Traditional therapies targeting androgen receptor (AR) signaling have limited efficacy. In a recent study, researchers investigated the potential of azolato-bridged dinuclear platinum(II) complexes, particularly 5-H-Y, as promising alternatives. Their findings highlight the complex's ability to inhibit AR signaling and induce cell death in prostate cancer cells, providing a new avenue for prostate cancer treatment.
Read more …Treating prostate cancer with novel platinum complex via targeting androgen receptor signaling