Some patients being treated with immune checkpoint inhibitors, a type of cancer immunotherapy, develop a dangerous form of heart inflammation called myocarditis. Researchers have now uncovered the immune basis of this inflammation. The team identified changes in specific types of immune and stromal cells in the heart that underlie myocarditis and pinpointed factors in the blood that may indicate whether a patient's myocarditis is likely to lead to death.
Read more …How cancer immunotherapy may cause heart inflammation in some patients
When performing a knee replacement surgery or total knee arthroplasty, doctors traditionally try to align the hip, knee, and ankle in a straight line, forming a neutral alignment, rather than replicating the patient's original alignment. To understand which approach is better, researchers have conducted a post-operation questionnaire comparing patient-reported outcomes to changes in knee alignment before and after surgery. Their findings may improve current surgical guidelines and patients' long-term quality of life.
Read more …Toward better surgical outcomes in patients undergoing knee replacement surgery
A new study of more than 1,000 adults, average age 33, found that meeting recommended physical activity guidelines isn't enough to counteract the 60-plus hours per week they spend sitting. To reduce heart disease risk and prevent accelerated aging, they need to sit less and work-out harder.
Read more …Prolonged sitting can sabotage health, even if you're young and active