Researchers found that peristaltic pump flow mechanically breaks supersaturation to induce amyloid formation by hen egg white lysozyme, a-synuclein, amyloid b 1-40, and b2-microglobulin. The high shear stresses induced by peristaltic flow likely reflect those that occur the blood and cerebrospinal fluid, suggesting that this factor could promote amyloidosis.

A study has provided new insights into the role of the brain as a crucial control center and the origin of obesity and type 2 diabetes. The hormone insulin plays a key role in the development of obesity. The brain's sensitivity to insulin is associated with long-term weight gain and unhealthy body fat distribution. What specific functions does insulin perform in the brain, and how does it affect individuals of normal weight?

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