The majority of mental health disorders manifest during adolescence and relate to a multiplex interplay of neurobiological and environmental factors. Instead of considering these factors in isolation, a newly developed manifold learning technique can model brain-environmental interactions, which vastly improves detection of existing mental health symptoms and prediction of future ones compared to current methods. The study underscores the importance of considering the adolescent brain in conjunction with the environment in which it develops.
Read more …New approach can help detect and predict mental health symptoms in teens

Aging is a major risk factor for neurodegenerative diseases, but the molecular mechanisms behind this relationship are not clear. In a recent study, researchers explored the role of PQBP3, a protein that helps stabilize the nuclear membrane, in cellular senescence and neurodegeneration. Their findings suggest that PQBP3 might be a promising therapeutic target for managing neurodegenerative diseases and the neuronal symptoms of aging.
Read more …Unveiling the molecular mechanisms linking aging with neurodegenerative diseases

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