Researchers have uncovered a key reason why a typically normal protein goes awry and fuels cancer. They found the protein NSD2 alters the function of the androgen receptor, an important regulator of normal prostate development. When androgen receptor binds with NSD2, it causes rapid cell division and growth leading to prostate cancer. The study may suggest a new way to therapeutically target prostate cancer.
Read more: Researchers identify factor that drives prostate cancer-causing genes
A new molecular engineering technique can precisely influence the development of organoids. Microbeads made of specifically folded DNA are used to release growth factors or other signal molecules inside the tissue structures. This gives rise to considerably more complex organoids that imitate the respective tissues much better and have a more realistic cell mix than before.
Read more: New molecular engineering technique allows for complex organoids
Investigators studying the nature of consciousness have successfully used a drug to identify the intricate brain geometry behind the unconscious state, offering an unprecedented look at brain structures that have traditionally been difficult to study.
Read more: How the brain's inner chamber governs our state of consciousness