A team of researchers has shown that a single, small strand of microRNA, or miRNA, known as let-7, governs the ability of T-cells to recognize and remember tumor cells. This cellular memory is the basis for how vaccines work. Boosting cellular memory to recognize tumors could help improve cancer therapies. The research suggests a new strategy for the next generation of cancer-fighting immunotherapies.
Read more …How a small strand of RNA is key to fighting cancer
Inflammation is the sign that our body is defending itself against an aggression. But when this response escalates, for example in the brain, it can lead to serious neurological or psychiatric diseases. A team investigated a marker protein targeted by medical imaging to visualize cerebral inflammation, but whose interpretation was still uncertain. The team reveals that a large quantity of this protein goes hand in hand with a large quantity of inflammatory cells, but its presence is not a sign of their overactivation. These results pave the way for optimal observation of neuroinflammatory processes and a re-reading of previous studies on the subject.
Read more …Marker for brain inflammation finally decoded