Health

Strokes: Offer patients three hours a day of rehab, NHS urged

Experts welcome the recommendation but ask if it is feasible for such a stretched health service.

NHS strikes: Consultants and government to hold talks to try to end dispute

Junior doctors and consultants on a picket line outside Queen Elizabeth Hospital on 2 October

The British Medical Association says strikes will be paused to allow time for the two sides to meet.

Familiarity breeds contempt for moral failings

People judge members of their own circles more harshly than they judge individuals from other groups for the same transgressions, new research has found.

Human Lung Chip leveraged to faithfully model radiation-induced lung injury

Researchers have developed a human in vitro model that closely mimics the complexities of radiation-induced lung injury (RILI) and radiation dose sensitivity of the human lung. Using a previously developed microfluidic human Lung Alveolus Chip lined by human lung alveolar epithelial cells interfaced with lung capillary cells to recreate the alveolar-capillary interface in vitro, the researchers recapitulated many of the hallmarks of RILI, including radiation-induced DNA damage in lung tissue, cell-specific changes in gene expression, inflammation, and injury to both the lung epithelial cells and blood vessel-lining endothelial cells. By also evaluating the potential of two drugs to suppress the effects of acute RILI, the researchers demonstrated their model's capabilities as an advanced, human-relevant, preclinical, drug discovery platform.

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