New methods to shape RNA molecules into circles could lead to more effective and long-lasting therapies, shows a new study. The advance holds promise for a range of diseases, offering a more enduring alternative to existing RNA therapies, which often suffer from short-lived effectiveness in the body.
Read more …Closing the RNA loop holds promise for more stable, effective RNA therapies
Researchers discovered that treating pancreatic cancer with a common chemotherapy drug makes immunotherapy more effective. Folinic acid elevates levels of two anti-cancer immune molecules within pancreatic tumors: natural killer T cells and type-I interferons. In mice, this led to a more effective immune response, slower tumor growth, and longer survival.
Read more …Old chemo drug, new pancreatic cancer therapy?
The surprising discovery that cellular protein G 13 may actually protect against -- rather than promote growth of -- the most commonly relapsing type of breast cancer signals potential for more effective and innovative treatments.
Read more …Key discovery advances fight to reduce breast cancer recurrence