A collaborative effort has shed valuable light on how monoamine neurotransmitters such as serotonin, dopamine, and now histamine help regulate brain physiology and behavior through chemical bonding of these monoamines to histone proteins, the core DNA-packaging proteins of our cells.

Scientists have taken a major step in understanding how animal brains make decisions, revealing a crucial role for electrical synapses in 'filtering' sensory information. The new research demonstrates how a specific configuration of electrical synapses enables animals to make context-appropriate choices, even when faced with similar sensory inputs.

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