How can we ensure that life-saving drugs or genetic therapies reach their intended target cells without causing harmful side effects? Researchers have taken an important step to answer this question. They have developed a method that, for the first time, enables the precise detection of nanocarriers -- tiny transport vehicles -- throughout the entire mouse body at a single-cell level.

Hepatitis E, a potentially serious viral liver disease, is transmitted through contaminated water. The risk is particularly high in populations with limited access to safe water and sanitation. In South Sudan, outbreaks have regularly ravaged camps for internally displaced persons and their host populations. Although a vaccine has been available since 2011, its 3-dose regimen makes it difficult to administer in such a context.

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