Researchers have identified a new potential target for the treatment of Alzheimer's disease -- PDE4B. The researchers observed that AD mice showed memory deficits in maze tests, but memory was unimpaired in AD mice with genetically reduced PDE4B activity.
Read more …New treatment target identified for Alzheimer's disease
Our bodies can maintain body temperature in cold environments. However, the detailed mechanism remains unclear. Researchers elucidated the molecular mechanism by which macrophages, a type of immune cells, control heat production in brown adipose tissue to increase the body temperature in response to cold.
Read more …Macrophages produce heat from brown adipose tissue in response to cold