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Monday, April 21, 2025

Antibody-drug conjugate found effective against brain metastases in patients with HER2-positive breast cancer

A drug that delivers chemotherapy directly to tumors has shown impressive activity against some of the hardest-to-reach cancer cells: those that have spread to the brain in patients with advanced HER2-positive breast cancer. The findings, from an international clinical trial, reinforce earlier findings of the benefits of the drug -- trastuzumab deruxtecan (T-DXd), an antibody-drug conjugate -- in these patients, trial leaders say.

Unveiling the math behind your calendar

In a world where organizing a simple meeting can feel like herding cats, new research reveals just how challenging finding a suitable meeting time becomes as the number of participants grows. The study dives into the mathematical complexities of this common task, offering new insights into why scheduling often feels so impossible.

Endometriosis pain leads to missed school and work in two-thirds of women with the condition, new study finds

Young millennial woman feeling unwell and leaning over on a bed clutching her stomach.

More than two-thirds of women with endometriosis missed school or work due to pain from the condition, in a study of more than 17,000 women between the ages of 15 and 44 in the U.S. That is a key finding of new research ^[1] published in the Journal of Endometriosis and Uterine Disorders.

Our study also found that Black and Hispanic women were less likely to be diagnosed with endometriosis compared with white women....

Residents in San Joaquin Valley breathe chemical pesticides, according to new study

A new study found 22% of adults and 10% of children who participated in an air-quality study in California's San Joaquin Valley were breathing detectable levels of pesticides.

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