A new study has revealed that areas of age-related damage in the brain relate to motor outcomes after a stroke -- a phenomenon that may be under-recognized in stroke research. The new observational study looked at the relationship between stroke recovery and white matter hyper-intensities (WMHs) -- areas of age-related damage in the brain's white matter, which represent vascular dysfunction and are known to impact cognitive functions.
Read more …New study reveals age-related brain changes influence recovery after stroke
Researchers have found a way to enhance and extend LN expansion, and study how this phenomenon affects both the immune system and efficacy of vaccinations against tumors. While the oversized LNs maintained a normal tissue organization, they displayed altered mechanical features and hosted higher numbers of various immune cell types that commonly are involved in immune responses against pathogens and cancers. Importantly, 'jump-starting' lymph node expansion prior to administering a traditional vaccine against a melanoma-specific model antigen led to more effective and sustained anti-tumor responses in mice.
Read more …Expanding a lymph node, boosting a vaccine