To speed up their growth, leukemia cells typically activate the recycling of cellular structures -- enabling them to dispose of defective components and better supply themselves with building materials. Researchers have now shown that leukemia cells with a very common mutation activate specific genes that are important for this recycling process. Their findings open up new therapeutic options for the future.

Researchers are investigating the potential of a painless, needle-free vaccine delivery by ultrasound. The method uses cavitation, which is the formation and popping of bubbles in response to a sound wave. Though initial in vivo tests reported 700 times fewer vaccine molecules were delivered by the cavitation approach compared to conventional injection, the cavitation approach produced a higher immune response. The researchers theorize this could be due to the immune-rich skin the ultrasonic delivery targets. The result is a more efficient vaccine that could help reduce costs and increase efficacy.

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