In 2024, state legislatures introduced an all-time record of 533 bills targeting LGBTQ+ populations[1]. These policies create a patchwork of legal landscapes that vary widely between and within states, affecting aspects of everyday life ranging from how kids learn and play to where adults live and work.

All of these policies have implications for the health of not only LGBTQ+ people but also the general public.

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New research has investigated the mechanism by which bivalency functions to poise genes for expression during cell differentiation, providing insight into a long-standing paradigm in the regulation of developmental gene expression, revealing a key mechanism that has so far eluded experimental scrutiny. These findings provide insight into the intricate cellular processes that control development, how cell types are specified from stem cells, and how cell identity is established. Deciphering these mechanisms is not only key to understand fundamental biology but will also ultimately pave the way for the development of regenerative medicine approaches.
Read more …Uncovering how developmental genes are held in a poised state

A team of physicists has developed a groundbreaking method for detecting congestive heart failure with greater ease and precision than previously thought possible. This multidisciplinary study, involving both cardiologists and computational physicists, builds on the team's earlier breakthroughs, for example, in predicting the risk of sudden cardiac death.
Read more …New computational method reveals congestive heart failure

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