Wednesday, May 14, 2025
Wednesday, May 14, 2025

Biologists developed a method for illuminating the intricate interactions of the synaptonemal complex in the nematode C. elegans. The authors identified a trio of protein segments that guide chromosomal interactions, and pinpointed the location where they interact with each other. Their novel method uses a technique known as genetic suppressor screening, which can serve as a blueprint for research on large cellular assemblies that resist traditional structural analysis.
Read more …Nematode proteins shed light on infertility

People who have more disrupted sleep in their 30s and 40s may be more likely to have memory and thinking problems a decade later, according to new research published in the January 3, 2024, online issue of Neurology , the medical journal of the American Academy of Neurology. The study does not prove that sleep quality causes cognitive decline. It only shows an association.
Read more …Even in midlife, disrupted sleep tied to memory, thinking problems later on

The blood-brain barrier blocks the entry of antibodies into the brain. This limits the potential use of antibody therapeutics to treat brain diseases, such as brain tumors. Elsewhere in the body, more than 100 United States Food and Drug Administration-approved therapeutic antibodies are used by medical teams to treat cancers and autoimmune, infectious and metabolic diseases. Now researchers report that the site-directed addition of an FDA-approved, biodegradable polymer at the hinge and near hinge regions of the therapeutic antibody trastuzumab effectively facilitated the brain delivery of this human monoclonal IgG1 antibody.
Read more …An enhanced brain delivery of antibodies heightens the potential to treat brain diseases

More Articles …

  1. Bacteria load their syringes
  2. Reprogrammed fat cells support tumor growth
  3. Foundation laid for improved diagnostic imaging of brain tumors
  4. Epilepsy drug shows promise in slowing joint degeneration in osteoarthritis
  5. Chronic childhood ear infections delay language development
  6. Acetaminophen use during pregnancy linked to language delays in children
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