Novel findings from a preclinical head-to-head comparison show that administering a COVID-19 vaccine as a nasal spray rather than a subcutaneous injection enhances the body's long-term immune memory, thereby increasing the vaccine's overall effectiveness. This research could pave the way for a COVID-19 vaccination strategy that depends on fewer boosters to achieve the same level of protection against SARS-CoV-2 viruses.
Read more …Scientists discover potential nasal COVID-19 vaccine candidate that offers better and longer...
Combining a biological heart and a silicone robotic pump, researchers created a biorobotic heart that beats like a real one, with a focus on a valve on the left side of the heart. The heart valve simulator can mimic the structure, function, and motion of a healthy or diseased heart, allowing surgeons and researchers to demonstrate various interventions while collecting real-time data.
Read more …A beating biorobotic heart aims to better simulate valves
Researchers have created the world's largest ancient human gene bank by analyzing the bones and teeth of almost 5,000 humans who lived across western Europe and Asia up to 34,000 years ago. By sequencing ancient human DNA and comparing it to modern-day samples, the international team of experts mapped the historical spread of genes -- and diseases -- over time as populations migrated. They found: The startling origins of neurodegenerative diseases including multiple sclerosis; why northern Europeans today are taller than people from southern Europe; and how major migration around 5,000 years ago introduced risk genes into the population in north-western Europe -- leaving a legacy of higher rates of MS today.
Read more …Ancient DNA reveals reason for high multiple sclerosis and Alzheimer's rates in Europe