Optimizing boosters: How COVID mRNA vaccines reshape immune memory after each dose

COVID-19 vaccines elicit strong T-cell responses, but clonal-resolution analyses of these responses have not previously been performed. To address this gap, a team of researchers investigated the T- cell receptor sequence and tracked it using trammer analysis, uncovering key insights into the dynamics of T-cell responses. This study can lead to improved next-generation vaccines.

COVID-19 vaccines elicit strong T-cell responses, but clonal-resolution analyses of these responses have not previously been performed. To address this gap, a team of researchers investigated the T- cell receptor sequence and tracked it using trammer analysis, uncovering key insights into the dynamics of T-cell responses. This study can lead to improved next-generation vaccines.

Read more https://www.sciencedaily.com/releases/2024/03/240308123303.htm