Fatty liver disease (steatotic liver disease, SLD for short) is increasingly causing failure of the liver as a vital organ. A team led by researchers has now discovered that a saturated fatty acid in blood vessels leads to the production of the signalling molecule SEMA3A, which closes the 'windows' in the blood vessels. This hinders the transport of fat from the liver to the adipose tissue. The researchers report that the windows open again and the fat in the liver is reduced when SEMA3A is inhibited.
Read more …New approach against fatty liver
Researchers have found a new function for an existing protein. They discovered that TIMP-1, a protein traditionally known to prevent damage to the body's cells and tissues, plays a critical role in the immune system's defense against cancer. The findings of the study could improve the effectiveness of current cancer immunotherapies.
Read more …New and crucial role discovered for a protein in the body's immunity against cancer
An artificial intelligence-powered method for detecting tumor DNA in blood has shown unprecedented sensitivity in predicting cancer recurrence. The new technology has the potential to improve cancer care with the very early detection of recurrence and close monitoring of tumor response during therapy.
Read more …Ultrasensitive liquid biopsy tech spots cancer earlier than standard methods
Results from a new phase 1 trial indicate that immunotherapy could be used to treat the most common form of colorectal cancer, also known as bowel cancer. Consistent responses to immunotherapy have been reported in patients with the most common type of colorectal tumors, known as MSS mCRC, with 61% of patients seeing their tumor shrink or remain stable after receiving treatment.
Read more …Successful trial for new colorectal cancer treatment