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Sunday, April 20, 2025

New 3D technique reveals precancerous pancreatic lesions

Researchers have developed a 3D genomic profiling technique to identify small precancerous lesions in the pancreas -- called pancreatic intraepithelial neoplasias (PanINs) -- that lead to one of the most aggressive, deadly pancreatic cancers.

EPA has lowered the screening level for lead in soil – here’s what that could mean for households across the US

As spring phases into summer across the U.S., kids are spending more time outdoors. Playing outside is healthy in all kinds of ways, but it also poses some risks. One that many families may not be aware of is exposure to lead in soil, which is still a serious problem, mainly in cities.

Children can be exposed to lead ^[1] by swallowing or inhaling soil while they are playing. Young children often put their hands in their...

Discovery of 'new rules of the immune system' could improve treatment of inflammatory diseases, say scientists

A single large population of healer cells, called regulatory T cells, is whizzing around our body -- not multiple specialist populations restricted to specific parts of the body as previously thought. These cells shut down inflammation and repair the collateral damage to cells caused after our immune system has responded to injury or illness. Tests, in mice, of a drug developed by the researchers showed that regulatory T cells can be attracted to specific body parts, boosted in number, and activated to suppress immune response and rebuild tissue. Current anti-inflammatory drugs used for this purpose suppress the body's whole immune system, making patients more vulnerable to infection. The discovery could lead to more targeted treatments, with fewer side-effects, for issues from lengthy COVID infections to autoimmune diseases like multiple sclerosis. Clinical trials in humans are now planned.

The declining diet of Japan's youth

Researchers performed a study to quantify highly processed food consumption and to investigate its association with diet quality among Japanese children and adolescents. Highly processed foods (HPFs) accounted for over one-fourth of the total energy intake amongst youths. Consumption was negatively associated with the intake of healthy foods, such as fruits, vegetables and pulses, and positively associated with the consumption of confectioneries.

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