Researchers reveal how DNA gyrase resolves DNA entanglements. The findings not only provide novel insights into this fundamental biological mechanism but also have potential practical applications. Gyrases are biomedical targets for the treatment of bacterial infections and the similar human versions of the enzymes are targets for many anti-cancer drugs. Better understanding of how gyrases work at the molecular level can potentially improve clinical treatments.
Read more …First step to untangle DNA: Supercoiled DNA captures gyrase like a lasso ropes cattle
What if changes in a person's stress levels could be detected while they sleep using wearable devices? A new study find changes in perceived stress levels reflected in sleep data -- an important step towards identifying biomarkers that may help flag individuals in need of support.
Read more …Scientists use wearable technology to detect stress levels during sleep