Biomedical engineers have developed a silk-based, ultrathin membrane that can be used in organ-on-a-chip models to better mimic the natural environment of cells and tissues within the body. When used in a kidney organ-on-a-chip platform, the membrane helped tissues grow to recreate the functionality of both healthy and diseased kidneys.
Read more …Silkworms help grow better organ-like tissues in labs
Researchers are developing a new therapeutic approach that uses nanoparticles for the treatment of skin and lung fibrosis, conditions that can result in severe damage to the body's tissues.
Read more …Potential treatment for fibrosis
Preliminary clinical data for glioblastoma multiforme patients enrolled in a Phase 1 clinical trial demonstrated that 92 percent of evaluable patients treated with INB-200 exceeded a median progression-free survival of seven months with concomitant temozolomide chemotherapy. The median follow-up was 11.7 months. This survival data along with radiographic improvements are indicative of positive treatment effects, which highlights the potential of IN8bio's genetically modified, chemotherapy-resistant gamma-delta T cells as a potential first-in-class therapy for patients with newly diagnosed glioblastoma.
Read more …Encouraging Phase 1 data for glioblastoma treatment
Little is yet known about the health effects of nanoparticles on pregnancy. An interdisciplinary team is currently analyzing the risks for babies in the womb. Using a lab model, the researchers were able to determine that certain nanoparticles impair the release of chemical messengers in the placenta and thus the formation of blood vessels.
Read more …Nanoparticles: Risk for babies in the womb