Researchers show that genetic traits influence the cellular composition of atherosclerotic plaques, which over time will affect the risk of such lesions to cause a stroke or heart attack. The new knowledge can be used to improve the risk assessment and treatment of patients with atherosclerosis in the future.
Read more …Mapping of atherosclerotic plaque cells may predict future risk of stroke or heart attack
Mortality attributable to air pollution and extreme temperatures is a major concern, and it is expected to heighten in the future. An international research team found that, under the most probable projection, annual mortality rates linked to air pollution and extreme temperatures could reach 30 million by the end of the century. The research, based on advanced numerical simulations, suggests a concerning trend: pollution-related deaths are expected to increase five-fold, while temperature-related mortality could rise seven-fold, posing a more critical health risk than air pollution for at least 20% of the world's population.
Read more …Climate change and air pollution could risk 30 million lives annually by 2100
Scientists have identified human antibodies capable of targeting the proteins responsible for severe malaria, potentially paving the way for new vaccines or treatments. Using organ-on-a-chip technology, researchers successfully demonstrated that these antibodies prevent infected red blood cells from adhering to vessel walls, a key driver of severe malaria symptoms. The antibodies neutralize a conserved region of the malarial protein PfEMP1, overcoming its notorious variability and shedding light on acquired immunity mechanisms. This interdisciplinary study, published in Nature, highlights the power of international teamwork in addressing major health challenges like malaria.
Read more …Stopping severe malaria by harnessing natural human antibodies