Researchers have unraveled how immune cells called microglia can transform and drive harmful processes like neuroinflammation in Alzheimer's disease. The study also integrates drug databases with real-world patient data to identify FDA-approved drugs that may be repurposed to target disease-associated microglia in Alzheimer's disease without affecting the healthy type.
Read more …Network-based analyses uncover how neuroinflammation-causing microglia in Alzheimer's disease form
People who climb too fast or too high risk acute altitude sickness, which can lead to life-threatening hypoxic brain injury. By using in vivo electrochemistry, researchers demonstrated that characteristic changes occur in the oxygen content of various brain regions before injury. The risk of brain damage could be predicted days in advance -- perhaps a new approach for detecting high-altitude hypoxic injury.
Read more …Early detection of high-altitude hypoxic brain injury