New way to force pathogenic proteins into degradation

A number of diseases are caused by proteins that have spun out of control. Unfortunately, so far, conventional drugs have been able to stop only a fraction of these troublemakers. A new class of drugs known as PROTACs holds great promise in pharmaceutical research. They mark proteins for targeted degradation by the cell's own protein disposal system.

A number of diseases are caused by proteins that have spun out of control. Unfortunately, so far, conventional drugs have been able to stop only a fraction of these troublemakers. A new class of drugs known as PROTACs holds great promise in pharmaceutical research. They mark proteins for targeted degradation by the cell's own protein disposal system.

Read more https://www.sciencedaily.com/releases/2023/12/231211114542.htm