A drug currently in clinical trials as a cancer therapy can also stimulate pancreatic beta cells to secrete insulin, revealing a previously unknown mechanism for insulin regulation in type 2 diabetes, according to a new study. The preclinical discovery provides a new chemical tool for probing the biology of diabetes, and could point the way toward better treatments for the disease.

Roughly two decades ago, a community-wide reckoning emerged concerning the credibility of published literature in the social-behavioral sciences, especially psychology. Several large scale studies attempted to reproduce previously published findings to no avail or to a much lesser magnitude, sending the credibility of the findings -- and future studies in social-behavioral sciences -- into question. 

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