Researchers report the development of a methodology to detect small amounts of potential tumor therapeutic targets, specificacally enzymes called kinases, that are present in biopsy samples. Therapies that directly inhibit cancer-promoting activities of some of these kinases have proven to be effective for patients in which individual driving kinases can be diagnosed.
Read more: Method improves detection of potential therapeutic tumor targets in human biopsies
A mouse study designed to shed light on memory loss in people who experience repeated head impacts, such as athletes, suggests the condition could potentially be reversed. The research in mice finds that amnesia and poor memory following head injury is due to inadequate reactivation of neurons involved in forming memories.
Read more: Amnesia caused by head injury reversed in early mouse study
This month, a group of stroke survivors in British Columbia will test a new technology designed to aid their recovery, and ultimately restore use of their limbs and hands. Participants will wear a new groundbreaking 'smart glove' capable of tracking their hand and finger movements during rehabilitation exercises.
Read more: 'Smart glove' can boost hand mobility of stroke patients
Supersulfides, many of which are produced by cysteinyl-tRNA synthetase (CARS), are essential compounds across many different lifeforms. However, the precise physiological roles of CARS-produced supersulfide are unclear. Now, using a strategically engineered yeast mutant with a deficient CARS gene, researchers from Japan have shown that supersulfides control cell longevity by mediating mitochondrial energy metabolism and regulating protein quality.
Read more: Unraveling the role of supersulfides in regulating mitochondrial function and longevity