Researchers have identified a new potential target for the treatment of Alzheimer's disease -- PDE4B. The researchers observed that AD mice showed memory deficits in maze tests, but memory was unimpaired in AD mice with genetically reduced PDE4B activity.
Read more: New treatment target identified for Alzheimer's disease
Our bodies can maintain body temperature in cold environments. However, the detailed mechanism remains unclear. Researchers elucidated the molecular mechanism by which macrophages, a type of immune cells, control heat production in brown adipose tissue to increase the body temperature in response to cold.
Read more: Macrophages produce heat from brown adipose tissue in response to cold