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Saturday, September 13, 2025

Unraveling the role of supersulfides in regulating mitochondrial function and longevity

Supersulfides, many of which are produced by cysteinyl-tRNA synthetase (CARS), are essential compounds across many different lifeforms. However, the precise physiological roles of CARS-produced supersulfide are unclear. Now, using a strategically engineered yeast mutant with a deficient CARS gene, researchers from Japan have shown that supersulfides control cell longevity by mediating mitochondrial energy metabolism and regulating protein quality.

Warning of further measles outbreaks as cases rise

Medics issue the warning after cases in the West Midlands rose by more than 30% in less than a week.

Cloned rhesus monkey created to speed medical research

Researchers say it will speed up drug testing but animal rights campaigners have grave concerns.

Your body already has a built-in weight loss system that works like Wegovy, Ozempic and Mounjaro – food and your gut microbiome

Wegovy, Ozempic and Mounjaro ^[1] are weight loss and diabetes drugs that have made quite a splash in health news ^[2]. They target regulatory pathways involved in both obesity and diabetes ^[3] and are widely considered breakthroughs for weight loss and blood

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