During a bout of influenza, B cells interact with other immune cells and then take different paths to defend the body. One path is the B cells that differentiate into lung-resident memory B cells, or lung-BRMs, that are critical for pulmonary immunity. These long-lived, non-circulating lung-BRMs migrate to the lungs from draining lymph nodes and reside there permanently as the first layer of defense that can quickly react to produce antibodies in a future infection.
Read more …Flu: Interferon-gamma from T follicular helper cells is required to create lung-resident memory B...
Scientists identify a new and surprising function of a membrane protein on the surface of cancer cells: It supports and stabilizes an important 'co-stimulatory' factor that enhances the activation of T cells, thus improving the immune response against the tumor.
Read more …A protein on cancer cells supports the immune response against tumors
The benefits of four measures of socioeconomic status (education, income, employment status and health insurance) on ideal heart health were greater for non-Hispanic white adults compared to Black, Hispanic and Asian adults in the U.S.
Read more …Socioeconomic status may be an uneven predictor of heart health