Self-folding polymers containing gadolinium forming nanosized complexes could be the key to enhanced magnetic resonance imaging and next-generation drug delivery. Thanks to their small size, low toxicity, and good tumor accumulation and penetration, these complexes represent a leap forward in contrast agents for cancer diagnosis, as well as neutron capture radiotherapy.
Read more …Breakthroughs in nanosized contrast agents and drug carriers through self-folding molecules
Mathematics, histopathology and genomics converge to confirm that the most aggressive clear cell renal cell carcinomas display low levels of intratumour heterogeneity, i.e. they contain fewer distinct cell types. The study supports the hypothesis that it would be advisable to apply therapeutic strategies to maintain high levels of cellular heterogeneity within the tumour in order to slow down the evolution of the cancer and improve human survival.
Read more …Mathematics supporting fresh theoretical approach in oncology