ETH Zurich researchers have developed a new method of magnetic resonance imaging (MRI) for the early detection and better monitoring of multiple sclerosis (MS). The method maps the myelin sheaths in the brain more precisely than was previously possible. The loss of myelin sheaths is a hallmark of MS. The new MRI method with its special head scanner could also be used by researchers to better visualise other solid tissue types such as connective tissue, tendons and ligaments.
Read more …Visualising multiple sclerosis with a new MRI procedure

Scientists discovered a pathway from mitochondrial DNA replication stress to immune system activation and inflammation, finding that endosomes responsible for disposing of dysfunctional mitochondrial DNA were leaking mitochondrial DNA into the cell and prompting the inflammatory immune response. The pathway provides new targets for therapeutics that disrupt inflammation during aging and disease.
Read more …Faulty DNA disposal system causes inflammation

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