CRISPR-Cas systems, defense systems in bacteria, have become a plentiful source of technologies for molecular diagnostics. Researchers have now expanded this extensive toolbox further. Their novel method, called PUMA, enables the detection of RNA with Cas12 nucleases, which naturally target DNA. PUMA promises a wide range of applications and high accuracy.
Read more …A new addition to the CRISPR toolbox: Teaching the gene scissors to detect RNA
Rigorous exercise before bed has long been discouraged, but researchers have now found short bursts of light activity can lead to better sleep.
Read more …Evening activity for better sleep
Delivery systems in body continuously move materials between cells. Hijacking these systems allowed scientists to improve loading and delivery of therapeutic proteins. Biophysical principles could be used to enable more cost-effective loading of biological cargo into cell-derived delivery systems. Engineered molecules loaded up to 240 times more protein than other loading methods.
Read more …Transporting precious cargo using the body's own delivery system