The majority of mental health disorders manifest during adolescence and relate to a multiplex interplay of neurobiological and environmental factors. Instead of considering these factors in isolation, a newly developed manifold learning technique can model brain-environmental interactions, which vastly improves detection of existing mental health symptoms and prediction of future ones compared to current methods. The study underscores the importance of considering the adolescent brain in conjunction with the environment in which it develops.
Read more …New approach can help detect and predict mental health symptoms in teens

Aging is a major risk factor for neurodegenerative diseases, but the molecular mechanisms behind this relationship are not clear. In a recent study, researchers explored the role of PQBP3, a protein that helps stabilize the nuclear membrane, in cellular senescence and neurodegeneration. Their findings suggest that PQBP3 might be a promising therapeutic target for managing neurodegenerative diseases and the neuronal symptoms of aging.
Read more …Unveiling the molecular mechanisms linking aging with neurodegenerative diseases

In a study using human breast cancer cells, scientists say they have potentially identified immune system white blood cells that appear to be the closest neighbors of breast cancer cells that are likely to spread. The researchers say the finding, focused on a white blood cell called a macrophage, may provide a new biological target for immunotherapies designed to destroy spreading cancer cells that are often markers for worsening disease.
Read more …Scientists identify potential new immune system target to head off the spread of breast cancer cells

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