Delivery systems in body continuously move materials between cells. Hijacking these systems allowed scientists to improve loading and delivery of therapeutic proteins. Biophysical principles could be used to enable more cost-effective loading of biological cargo into cell-derived delivery systems. Engineered molecules loaded up to 240 times more protein than other loading methods.
Read more …Transporting precious cargo using the body's own delivery system
Our immune system is always on alert, detecting and eliminating pathogens and cancer cells. Cellular control mechanisms cause diseased cells to present antigens on their surface like signs for the immune system. For analysis of the necessary complex antigen processing and transport processes in real time, researchers have developed a 'cage' that is opened with light to release trapped antigens at a specific place and time.
Read more …Immune system in the spotlight