An international research team has identified key genetic factors that confer protective effects against Alzheimer's disease (AD) through a comprehensive genetic analysis of East Asian populations, including Chinese and Japanese, as well as European populations. This groundbreaking discovery sheds light on how these genetic factors can exert protective effects, unveiling the biological mechanisms underlying AD pathogenesis.

Maternal stress could leave epigenetic imprints on genes in the placenta associated with cortisol -- a necessary hormone for fetal development -- and this would affect the baby's development from very early stages. The study suggests that a mother's emotional wellbeing during pregnancy is not only important for her, but could also influence the future health of her baby.

New assessment warns area the size of the USA will become too hot during extreme heat events for even healthy young humans to maintain a safe body temperature if we hit 2 degrees Celsuis above preindustrial levels. For those aged over 60, the same 2 degree rise would see more than a third of the planet's land mass cross this critical 'overheating' threshold.

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