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Tuesday, June 10, 2025

Fat-rich fluid fuels immune failure in ovarian cancer

New research has uncovered how lipid-rich fluid in the abdomen, known as ascites, plays a central role in weakening the body's immune response in advanced ovarian cancer. The findings offer new insights into immune suppression in ovarian cancer and open promising avenues for future immunotherapy approaches. Over 70% of patients with ovarian cancer are diagnosed at an advanced stage, often presenting with large volumes of ascites. This ascites fluid not only supports the spread of cancer throughout the abdominal cavity but also significantly impairs the body's immune defenses. Understanding how ascites affects the immune system is important for developing better treatments that use the immune system to fight cancer.

A more realistic look at DNA in action

By creating a more true-to-life representation of DNA's environment, researchers have discovered that strand separation may take more mechanical force than the field previously believed.

Novel, needle-free, live-attenuated influenza vaccines with broad protection against human and avian virus subtypes

A research team has achieved a significant breakthrough in developing broadly protective, live-attenuated influenza vaccines (LAIV). These innovative LAIV platforms offer potential to develop universal influenza vaccines that induce a more robust immune response against various virus subtypes, including both human and avian strains.

Nitrous oxide recreational use is linked to brain damage and sudden death − but ‘laughing gas’ is still sold all over the US

A man, outdoors and at a public gathering, is inhaling through a balloon.

The U.S. Food and Drug Administration is warning Americans ^[1] about the ever-increasing and potentially deadly recreational use of nitrous oxide products, particularly among young people.

Marketed with names like “Galaxy Gas” and “Miami Magic,” and often sold in steel cartridges known as “whippets ^[2],” these products are cheap and readily available ^[3] at gas stations, convenience stores, smoke shops and major retail...

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