Embryonic stem (ES) cells are pluripotent stem cells that can produce all cell types of an organism. ES cells proliferate rapidly and have been thought to experience high levels of intrinsic replication stress. However, a recent report challenges this assumption by providing a detailed molecular investigation of replication dynamics in these cells.
Read more …DNA replication mechanism in pluripotent stem cells
Researchers have uncovered DNA markers associated with retroelements, remnants of ancient viral genetic material, in our genes that act as highly accurate epigenetic clocks predicting chronological age. The results support the idea that certain retroelements in the human genome may be involved in aging.
Read more …Potential link between DNA markers and aging process
Researchers have found a new way to manage the receptors that control the sense of touch, which could lead to treating chronic pain more effectively. Using phosphatidic acid as a regulator of the sense of touch may lead to better pain relief.
Read more …New way to control the sense of touch