Brown fat cells convert energy into heat -- a key to eliminating unwanted fat deposits. In addition, they also protect against cardiovascular diseases. Researchers have now identified the protein EPAC1 as a new pharmacological target to increase brown fat mass and activity. The long-term aim is to find medicines that support weight loss.
Read more …Main regulator for the body`s 'oven' discovered
More than 65,000 men fall ill with prostate cancer each year in Germany. Twelve thousand of them develop a treatment-resistant form which eventually ends in death. Now, a team of researchers has developed an active substance that might in future represent a new treatment option. This substance, known as KMI169, targets an enzyme that plays an important role in the development of prostate cancer.
Read more …Prostate cancer: Newly-developed inhibitor shows massive potential
From a wartime spread of antimicrobial resistant disease in Ukraine, to superbugs in China causing 'white lung' pneumonia in children, 2023 brought no shortage of new evidence that antimicrobial resistance (AMR) continues to be a pressing problem globally, and this pattern shows no sign of abating in 2024 unless a radical shift occurs. To truly tackle the issue of AMR, researchers with the Global Strategy Lab (GSL) argue it needs to be understood as a socio-ecological challenge that accepts AMR as a phenomenon stemming from natural evolutionary processes. In other words, the war on bugs can't be won; what's needed is a major change in how people live with it.
Read more …War on superbugs can't be won, researchers declare