Researchers describe the full molecular structure of the phage DEV. DEV infects and lyses Pseudomonas aeruginosa bacteria, an opportunistic pathogen in cystic fibrosis and other diseases. DEV is part of an experimental phage cocktail developed to eradicate P. aeruginosa infection in pre-clinical studies. Bacterial viruses, known as phages, are the most abundant biological entities on the planet and are increasingly used as biomedicines to eradicate antibiotic-resistant pathogenic bacteria.
Read more …Structural biology analysis of a Pseudomonas bacterial virus reveals a genome ejection motor
Expanding access to new, highly effective weight-loss medications could prevent more than 40,000 deaths a year in the United States, according to a study. The findings highlight the critical need to remove existing barriers that are hindering people's access to effective weight loss treatments and impeding public health efforts to address the national obesity crisis, the researchers said. According to the U.S. Centers for Disease Control and Prevention, about 74% of Americans are considered overweight, with about 43% of those individuals considered obese.
Read more …Expanding access to weight-loss drugs could save thousands of lives a year
Developing edge-computing and AI capabilities from wearable sensors enhances their intelligence, critical for the AI of Things, and reduces power consumption by minimizing data exchange between sensory terminals and computing units. This enables wearable devices to process data locally, offering real-time processing, faster feedback, and decreased reliance on network connectivity and external devices, thereby enhancing efficiency, privacy, and responsiveness in applications like health monitoring, activity tracking, and smart wearable technology.
Read more …Soft microelectronics technologies enabling wearable AI for digital health