Microorganisms produce a wide variety of natural products that can be used as active ingredients to treat diseases such as infections or cancer. The blueprints for these molecules can be found in the microbes' genes, but often remain inactive under laboratory conditions. A team of researchers has now developed a groundbreaking genetic method that leverages a natural bacterial mechanism for the transfer of genetic material and uses it for the production of new active ingredients.
Read more …Activating the hidden pharmaceutical potential of bacteria
Researchers have revealed the molecular structure of TRACeR-I, a protein platform for reprogramming immune responses. A better understanding of its structure may help optimize designs for the platform, which can be used to develop cancer treatments by either directly modifying immune cells or by creating proteins that help immune cells locate cancer cells.
Read more …New immunotherapy platform with increased potential to target cancer cells
A new study of plant-based drinks reveals a common issue: they are lacking in proteins and essential amino acids compared to cow's milk. The explanation lies in their extensive processing, causing chemical reactions that degrade protein quality in the product and, in some cases, produce new substances of concern.
Read more …How chemical reactions deplete nutrients in plant-based drinks