Researchers have solved a cellular mystery that may lead to better therapies for colorectal and other types of cancer. A professor of pediatrics-developmental biology and an assistant professor of molecular, cellular, and developmental biology have shown the importance of the H3K36 methylation process in regulating plasticity and regeneration in intestinal cells.
Read more …'Switch' allows intestinal cells to regenerate after injury
In 2010, a researcher was pouring over research data when he discovered something he thought was odd: His data showed that at 6 months of age, formula-fed babies born of mothers who were categorized as medically obese weighed about 5% units less fat than breastfed babies in the same dataset. That discovery struck him as unusual and led him on a research journey to better understand breast milk. Now, he's studying the connections between maternal gestational diabetes, breastfeeding and infant health.
Read more …Milk as Medicine: Breast Milk Transforms Challenges into Triumphs
Even with significant expansion in the global market for antibodies used in clinical care and research, scientists recognize that there is still untapped potential for finding new antibodies. Many proteins group together in what are called protein complexes to carry out biological functions. The traditional method of generating antibodies by immunizing animals struggles to make antibodies related to these protein complexes. Scientists have now demonstrated that fusing protein complexes together adds stability during immunization and enables antibody generation.
Read more …Engineering antibodies with a novel fusion protein