CAR-T-cell therapy without side effects? Researchers show results in preclinical models

Some patients have experienced incredible recoveries after CAR-T-cell therapy. But they've also endured incredibly strong and scary side effects, in part because of the lymphodepleting chemotherapy that is performed before the CAR-T-cells are reinfused. What if CAR-T-cell therapy could be performed without lymphodepleting chemotherapy?

Some patients have experienced incredible recoveries after CAR-T-cell therapy. But they've also endured incredibly strong and scary side effects, in part because of the lymphodepleting chemotherapy that is performed before the CAR-T-cells are reinfused. What if CAR-T-cell therapy could be performed without lymphodepleting chemotherapy?

Read more https://www.sciencedaily.com/releases/2023/09/230907162605.htm