Why do lymphatic vessels form a jigsaw puzzle-like pattern?

While researchers have long been familiar with the surface structure of lymphatic vessels, a groundbreaking study has now focused on their jigsaw puzzle-like pattern. This arrangement helps cells tolerate changes in fluid pressure, such as swelling. Similar cell shapes are found on the surface of plant leaves, and the principle has been employed in human-led design as well.

While researchers have long been familiar with the surface structure of lymphatic vessels, a groundbreaking study has now focused on their jigsaw puzzle-like pattern. This arrangement helps cells tolerate changes in fluid pressure, such as swelling. Similar cell shapes are found on the surface of plant leaves, and the principle has been employed in human-led design as well.

Read more https://www.sciencedaily.com/releases/2025/03/250320145039.htm