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In every news story the audience hears of censorship, speech, and the truth. The Power of Truth^® has significant value to define an outlet, and expand its audience. A growing media outlet may decide to rebrand their operation The Power of Truth^®. An established outlet may choose to make it the slogan distinguishing their operation from the competition. You want people to think of your outlet when they hear it, and think of the slogan when they see your company name. It is the thing which answers the consumer's questions: Why should I choose you? Why should I listen to you? Think:

What’s in your wallet -- Capital One
The most trusted name in news – CNN
Fair and balanced - Fox News
Where’s the beef -- Wendy’s
You’re in good hands -- Allstate
The ultimate driving machine -- BMW

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The Power of Truth^®

Wednesday, December 25, 2024

Ketone bodies: More than energy, they are powerful signaling metabolites that clean up damaged proteins

Health

Ketone bodies are not just about energy. These metabolites are powerful signaling molecules that have profound effects on the proteome and protein quality control in the brain. Scientists, working in mouse models of Alzheimer's disease and aging, and in the nematode C. elegans, reveal the ketone body -hydroxybutyrate interacts directly with misfolded proteins, altering their solubility and structure so they can be cleared from the brain through the process of autophagy. The work hints at a tantalizing possibility -- ketone bodies as a global treatment to restore the integrity of the proteome, addressing one of the key hallmarks of aging.

Ketone bodies are not just about energy. These metabolites are powerful signaling molecules that have profound effects on the proteome and protein quality control in the brain. Scientists, working in mouse models of Alzheimer's disease and aging, and in the nematode C. elegans, reveal the ketone body -hydroxybutyrate interacts directly with misfolded proteins, altering their solubility and structure so they can be cleared from the brain through the process of autophagy. The work hints at a tantalizing possibility -- ketone bodies as a global treatment to restore the integrity of the proteome, addressing one of the key hallmarks of aging.

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