Stirred, not shaken: Scientists uncover how transcription drives motion within the genome

A team of scientists has discovered surprising connections among gene activity, genome packing, and genome-wide motions, revealing aspects of the genome's organization that directly affect gene regulation and expression. The findings bolster our understanding of the mechanics behind transcription-dependent motions of single genes -- the dysfunction of which may lead to neurological and cardiovascular disorders as well as to cancer.

A team of scientists has discovered surprising connections among gene activity, genome packing, and genome-wide motions, revealing aspects of the genome's organization that directly affect gene regulation and expression. The findings bolster our understanding of the mechanics behind transcription-dependent motions of single genes -- the dysfunction of which may lead to neurological and cardiovascular disorders as well as to cancer.

Read more https://www.sciencedaily.com/releases/2024/10/241022132836.htm